On a big weekend of women’s domestic action across Europe there is no question what the biggest game of the week will be.
Allianz Premier 15s champions Harlequins travel to current leaders Saracens in a rematch of last season’s final.
On that occasion, Quins sprung a surprise in defeating the side who had won each of the first two editions of the competition.
That win came despite losing skipper Rachael Burford to injury early on but she is back and could be crucial for a Quins team who have won four in a row in all competitions since a 29-22 loss to Sarries in October and will be able to rely on the likes of Shaunagh Brown to try to get the better of Saracens up front.
While that is a big game on Sunday, Bristol Bears will be hoping to move temporarily into top spot on Saturday when they travel to Worcester Warriors.
Bears have lost just once in the league all season but will be without prop Simi Pam who has suffered a knee injury that will keep her sidelined for three months.
Elsewhere, fourth-placed Exeter Chiefs welcome Gloucester-Hartpury in a game that could have play-off implications come the end of the season while Wasps host winless DMP Sharks and Sale Sharks travel to Loughborough Lightning.
Across in France, Montpellier and Stade Bordelais will be looking to take advantage of Blagnac not playing this week to strengthen their position in Pool 2 of the Elite 1.
Montpellier travel to Lille Métropole Villeneuvois currently sitting top of the table but level on points with Blagnac.
Bordeaux are two points back but with a game in hand, having won five from five ahead of their clash with Lyon.
In Pool 1, Toulouse, who boast World Player of the Year nominee Laure Sansus, are five from five and will hope to make it six against Stade Français who are currently third in the table.
Over in Italy, Valsugana Rugby Padova will be looking to continue their perfect start to the season as they travel to CUS Milano having racked up 71 tries in six matches so far this campaign.
Elsewhere nearest challengers Villorba are away to CUS Torino.
