Ireland have never lost to the Flying Fijians and after their superb Autumn Nations Series win over South Africa, Andy Farrell’s men will be determined to keep building momentum.
The two sides have only met in four Test matches, the latest in 2017 the closest the Pacific Island nation have come to claiming victory.
Ian Keatley slotted two late penalties to clinch a 23-20 Autumn Internationals win with Ireland head coach Joe Schmidt naming a largely inexperienced starting XV that day.
Flying Fijian head coach Vern Cotter saw his team put in a fine first half performance last Saturday, heading into the interval 14-12 down against Scotland before slipping to a 28-12 defeat.
Farrell, meanwhile, was beaming after the world number ones edged the Springboks 19-16 at the Aviva Stadium last weekend.
Furlong to lead out Ireland against Fiji
Tadhg Furlong is the 109th player to captain Ireland as he makes his 62nd Test appearance for Ireland.
The prop is one of six players to retain their place from the win over South Africa, with Tadhg Beirne and Caelan Doris the other forwards lining up again.
While Furlong is not the first prop to captain his country, the last one to do so was Simon Best against Argentina in 2007.
Doris is shifted to blindside from No.8 as Jack Conan comes in and Jeremy Loughman will make his debut for Ireland at loosehead.
Cian Prendergast and Jack Crowley could also earn their first senior international caps from the replacements bench after starting matches in the Māori Series over the summer.
Also involved against the NZ Māori during the summer are starters Jimmy O’Brien, Stuart McCloskey, Loughman, Kieran Treadwell and Nick Timoney.
In the backs, Robbie Henshaw starts at outside centre and there is a fresh half-back combination with Jamison Gibson Park and Joey Carbery named scrum-half and fly-half respectively.
The wingers are unchanged, with Robert Baloucoune and Mack Hansen starting in the back three alongside O’Brien.
Teams
Ireland: 15. Jimmy O’Brien, 14. Robert Baloucoune, 13. Robbie Henshaw, 12. Stuart McCloskey, 11. Mack Hansen, 10. Joey Carbery, 9. Jamison Gibson Park; 1. Jeremy Loughman, 2. Rob Herring, 3. Tadhg Furlong (captain), 4. Kieran Treadwell, 5. Tadhg Beirne, 6. Caelan Doris, 7. Nick Timoney, 8. Jack Conan
Replacements: 16. Dan Sheehan, 17. Cian Healy, 18. Tom O’Toole, 19. Cian Prendergast, 20. Max Deegan, 21. Craig Casey, 22. Jack Crowley, 23. Garry Ringrose
Flying Fijians: 15 Setareki Tuicuvu, 14 Jiuta Wainiqolo, 13 Waisea Nayacalevu, 12 Kalaveti Ravouvou, 11 Vinaya Habosi, 10 Teti Tela, 9 Frank Lomani; 1 Eroni Mawi, 2 Sam Matavesi, 3 Manasa Saulo, 4 Isoa Nasilasila, 5 Ratu Leone Rotuisolia, 6 Albert Tuisue, 7 Levani Botia, 8 Viliame Mata
Replacements: 16 Mesulame Dolokoto, 17 Livai Natave, 18 Lee-Roy Atalifo, 19 Apisalome Ratuniyarawa, 20 Johnny Dyer, 21 Simione Kuruvoli, 22 Ben Volavola, 23 Adrea Cocagi
