Arguably, the scrum-half's finest moment for England came as he started in the 2016 Championship match against France, helping to steer Eddie Jones's side to the Grand Slam
His journey in the game has been nothing short of remarkable. Beginning with his proud roots in Leeds, Care rose through the ranks to become one of the most celebrated players in the country. He has made an astonishing record 369 appearances for Harlequins, with whom he was won two Premiership titles.
Throughout an international career that was recently punctuated by a two-year spell in selection wilderness, Care has showcased his talents on some of rugby's greatest stages - and none, in his opinion, grander than the Guinness Men's Six Nations.
His controlled performances in the Championship have at times reached exceptional levels, while his 100th cap was written in the stars in 2024 when he came off the bench to reignite his team against heavy favourites Ireland, providing Harlequins teammate Marcus Smith with the pass for the winning drop goal.
“To play for England once was a dream come true. Never in my wildest dreams did I think I’d get the opportunity to do it over 100 times.
“After a lot of reflection in the past few months, the time feels right for myself and the team to retire from international rugby. The past 12 months in this England team have been my favourite, making memories that my family and I will cherish and remember forever.
“I’m unbelievably proud to be English and to have had the privilege to represent this amazing country over the past 16 years. The team is in a really exciting place and there are some incredible young nines out there that I can’t wait to watch and support how they take the team forward.
In a video message announcing the news, Care said:
“To Steve, Jamie, the coaches and the whole back room staff, thank you for believing in me. I know this team is going to do unbelievable things.
“I want to thank all the England fans from the bottom of my heart who have supported me and the team unconditionally throughout the years, all over the world. It means the world and nothing will ever beat the feeling of walking out to all of you at Twickenham.
“Thank you to every coach who picked me, dropped me, picked me again, loved me or hated me. Hopefully I have shown that you should never give up.
“To Jodie, Blake, Koha, Rocco and all the Care clan, I’m so grateful for all the sacrifices you have made to let me live my dream. I hope I made you proud.
“All good things must come to an end.”