Virimi Vakatawa will make his return for France in the centres against England at Twickenham as one of four changes for Les Bleus.
The centre had missed the start of the Guinness Six Nations with a knee injury but made his return to action last weekend with Racing 92.
He comes in for Arthur Vincent, who was not available, while Teddy Thomas replaces the injured Gabin Villière on the wing.
Up front, lock Romain Taofifenua takes the place of Bernard Le Roux, who was ruled out this week, while Dylan Cretin is preferred to Anthony Jelonch in the back row.
In the half-backs, Antoine Dupont is fit to take his place and will link up with Matthieu Jalibert once again.
Jalibert keeps his spot despite the return of Romain Ntamack, who comes onto the bench where France have gone for a 6-2 split between forwards and backs.
Hooker Camille Chat is also back fit and among the replacements, while lock Cyril Cazeaux will make his first appearance in the Championship if called upon from the bench, as will his Bordeaux teammate Cameron Woki.
Les Bleus have won two games out of two so far in the Championship but have not beaten England at Twickenham in the Guinness Six Nations since 2005.
They will be looking to put an end to that streak as they did in Round 2 against Ireland, when they won in Dublin for the first time in a decade.
France team to face England:
15. Brice Dulin (Stade Rochelais) 14. Teddy Thomas (Racing 92) 13. Virimi Vakatawa (Racing 92) 12. Gaël Fickou (Stade Français) 11. Damian Penaud (ASM Clermont) 10. Matthieu Jalibert (Union Bordeaux-Bègles) 9. Antoine Dupont (Stade Toulousain)
1. Cyril Baille (Stade Toulousain) 2. Julien Marchand (Stade Toulousain) 3. Mohamed Haouas (Montpellier) 4. Romain Taofifenua (RC Toulon) 5. Paul Willemse (Montpellier) 6. Dylan Cretin (Lyon OU) 7. Charles Ollivon (RC Toulon) 8. Grégory Alldritt (Stade Rochelais)
Replacements
16. Camille Chat (Racing 92) 17. Jean-Baptiste Gros (RC Toulon) 18. Dorian Aldegheri (Stade Toulousain) 19. Cyril Cazeaux (Union Bordeaux-Bègles) 20. Cameron Woki (Union Bordeaux-Bègles) 21. Anthony Jelonch (Castres Olympique) 22. Baptiste Serin (RC Toulon) 23. Romain Ntamack (Stade Toulousain)
