Captain Marlie Packer is back in the seven jersey, meaning a switch from back row to lock for Zoe Aldcroft, while Lark Atkin-Davies returns at hooker.
The backline remains the same for the third match in a row with the back three of Jess Breach Abby Dow and Ellie Kildunne scoring five of England’s eight tries in the 46-0 victory over Scotland last time out.
Seventeen of the 23 were involved in last year’s Grand Slam-deciding Twickenham clash with France.
Over 46,500 supporters will be in attendance for the round four match against former England assistant coach Scott Bemand’s Ireland side.
Red Roses team to take on Ireland
15 Ellie Kildunne (Harlequins, 41 caps); 14 Abby Dow (Trailfinders Women, 43 caps); 13 Megan Jones (Leicester Tigers, 19 caps), 12 Tatyana Heard (Gloucester-Hartpury, 20 caps); 11 Jess Breach (Saracens, 36 caps); 10 Holly Aitchison (Bristol Bears, 28 caps), 9 Natasha Hunt (Gloucester-Hartpury, 70 caps); 1 Hannah Botterman (Bristol Bears, 45 caps), 2 Lark Atkin-Davies (Bristol Bears, 56 caps), 3 Maud Muir (Gloucester-Hartpury, 28 caps); 4 Zoe Aldcroft (Gloucester-Hartpury, 51 caps), 5 Rosie Galligan (Saracens, 16 caps); 6 Sadia Kabeya (Loughborough Lightning, 16 caps), 7 Marlie Packer (Saracens, 102 caps) - captain, 8 Alex Matthews (Gloucester-Hartpury, 65 caps)
Replacements
16 Connie Powell (Harlequins, 17 caps), 17 Mackenzie Carson (Gloucester-Hartpury, 13 caps), 18 Kelsey Clifford (Saracens, 6 caps), 19 Morwenna Talling (Sale Sharks, 11 caps), 20 Maddie Feaunati (Exeter Chiefs, 3 caps), 21 Lucy Packer (Harlequins, 19 caps), 22 Emily Scarratt (Loughborough Lightning, 109 caps), 23 Sydney Gregson (Saracens, 5 caps)
